Aging & longevity · Sleep
Epitalon, simplified.
Also called Epithalon, AEDG
Early researchA four-building-block peptide famous in anti-aging circles for its effect on telomeres, the caps on your DNA.
- Size
- 4 amino acids
- How it is taken
- Injection
- Status
- Research compound, under FDA review
- Available sizes
- Vials: 10 mg, 20 mg, 30 mg, 35 mg, 50 mg
What is it?
Epitalon was designed in Russia based on an extract from the pineal gland, the part of the brain that makes melatonin.
Got a vial? See how it mixes
Tap your vial size to watch how it is mixed and see exactly what each mark on the syringe holds.
What studies show
- In the labIn human cells, it switched on telomerase, the enzyme that rebuilds telomeres.
- In animalsSome mice and fruit flies lived longer in studies.
- In peopleSmall studies in older adults, mostly from one research group, reported better melatonin rhythms.
What we don’t know yet
- Almost all research comes from one group and has not been independently repeated.
- Whether it extends life in people.
Side effects and cautions
- Very little human safety data.
Is it legal?
Not FDA-approved. Reviewed for insomnia by an FDA advisory committee in July 2026.
Dosage & schedule evidence
How to read published schedules
Third-party protocol charts are not established clinical dosing standards. The evidence for safe and effective human dose, frequency, and duration may be limited or absent.
| Measurement | Meaning |
|---|---|
| 1 mg | 1,000 mcg (mass) |
| 100 U-100 units | 1 mL (volume, not dose) |
Read third-party published protocols ↗ for context. North Star does not validate these schedules.
Consult your doctor before considering any peptide for personal use. Educational only, not administration guidance.
Common questions
What is Epitalon?
A four-building-block peptide famous in anti-aging circles for its effect on telomeres, the caps on your DNA. Epitalon was designed in Russia based on an extract from the pineal gland, the part of the brain that makes melatonin.
What does the research say about Epitalon?
In human cells, it switched on telomerase, the enzyme that rebuilds telomeres. Some mice and fruit flies lived longer in studies. Small studies in older adults, mostly from one research group, reported better melatonin rhythms.
Is Epitalon FDA approved?
Not FDA-approved. Reviewed for insomnia by an FDA advisory committee in July 2026.
What are the side effects of Epitalon?
Very little human safety data.
Related peptides
Not sure where to start?
Answer 8 quick questions and see which peptides the research points to for your goal.
Already know you want Epitalon? Ask Mark about it →
This page explains published research in plain language. It is not medical advice, a diagnosis, or a recommendation to take anything, and it does not give dosing. Most peptides here are not FDA-approved, and products sold online vary widely in purity. Rules around peptides are changing, so check the current status and talk with a licensed clinician before starting anything. Last reviewed 2026-10-19.