Muscle & recovery · Sleep · Aging & longevity
CJC-1295, simplified.
Also called With or without DAC; Mod GRF(1-29), often paired with ipamorelin
Human studiesA lab-made signal that nudges your body to release more growth hormone for days at a time.
- Size
- 29 amino acids
- How it is taken
- Injection
- Status
- Compounded only, not approved
- Available sizes
- Vials: With DAC: 2 mg, 5 mg, No DAC: 2 mg, 5 mg, 10 mg
What is it?
CJC-1295 is a modified version of the body’s growth-hormone-releasing signal (GHRH). It comes in two forms. “With DAC” has an add-on that lets it hitch a ride on blood proteins, so it lasts about a week. “No DAC” (also called modified GRF 1-29) lasts about 30 minutes and gives a short, more natural pulse, which is why it is the version usually paired with ipamorelin.
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What studies show
- In peopleIn small studies of healthy adults, one injection raised growth hormone levels several times over and kept IGF-1 higher for about a week or more.
What we don’t know yet
- Whether higher growth hormone from CJC-1295 builds muscle or improves health in real life.
- Long-term safety. Its drug development was stopped years ago.
Side effects and cautions
- Flushing, water retention and tingling are reported.
- Higher growth hormone can raise blood sugar.
- Banned in sport by WADA.
Is it legal?
Not FDA-approved. In 2026, HHS announced plans to let licensed compounding pharmacies make it with a prescription.
Dosage & schedule evidence
How to read published schedules
Third-party protocol charts are not established clinical dosing standards. The evidence for safe and effective human dose, frequency, and duration may be limited or absent.
| Measurement | Meaning |
|---|---|
| 1 mg | 1,000 mcg (mass) |
| 100 U-100 units | 1 mL (volume, not dose) |
Read third-party published protocols ↗ for context. North Star does not validate these schedules.
Consult your doctor before considering any peptide for personal use. Educational only, not administration guidance.
Common questions
What is CJC-1295?
A lab-made signal that nudges your body to release more growth hormone for days at a time. CJC-1295 is a modified version of the body’s growth-hormone-releasing signal (GHRH). It comes in two forms. “With DAC” has an add-on that lets it hitch a ride on blood proteins, so it lasts about a week. “No DAC” (also called modified GRF 1-29) lasts about 30 minutes and gives a short, more natural pulse, which is why it is the version usually paired with ipamorelin.
What does the research say about CJC-1295?
In small studies of healthy adults, one injection raised growth hormone levels several times over and kept IGF-1 higher for about a week or more.
Is CJC-1295 FDA approved?
Not FDA-approved. In 2026, HHS announced plans to let licensed compounding pharmacies make it with a prescription.
What are the side effects of CJC-1295?
Flushing, water retention and tingling are reported. Higher growth hormone can raise blood sugar. Banned in sport by WADA.
Comes in these blends
- CJC-1295 (no DAC) + Ipamorelin (5/5 mg vial): CJC-1295 + Ipamorelin
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This page explains published research in plain language. It is not medical advice, a diagnosis, or a recommendation to take anything, and it does not give dosing. Most peptides here are not FDA-approved, and products sold online vary widely in purity. Rules around peptides are changing, so check the current status and talk with a licensed clinician before starting anything. Last reviewed 2026-10-19.