Weight loss
5-Amino-1MQ, simplified.
Also called NNMT inhibitor (not a peptide)
Early researchA small molecule that blocks an enzyme called NNMT, which is more active in fat cells. It shrank fat in mice but has not been tested in people.
- Size
- Small molecule, not a peptide
- How it is taken
- Oral capsule or injection
- Status
- Research compound
- Available sizes
- Vials: 10 mg · Capsules: 50 mg
What is it?
NNMT is an enzyme that is more active in fat tissue, especially with obesity. Blocking it appears to make fat cells burn more energy. 5-Amino-1MQ is often grouped with peptides but is actually a much smaller molecule.
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What studies show
- In animalsObese mice on a high-fat diet lost fat mass and had smaller fat cells, without eating less.
- In the labIn fat cells in the lab, it raised energy use and reduced fat storage.
What we don’t know yet
- Whether any of this happens in people. There are no published human trials.
- Safety in people.
Side effects and cautions
- No human safety data.
- Product quality varies widely.
Is it legal?
Not FDA-approved for human use.
Dosage & schedule evidence
How to read published schedules
Third-party protocol charts are not established clinical dosing standards. The evidence for safe and effective human dose, frequency, and duration may be limited or absent.
| Measurement | Meaning |
|---|---|
| 1 mg | 1,000 mcg (mass) |
| 100 U-100 units | 1 mL (volume, not dose) |
Read third-party published protocols ↗ for context. North Star does not validate these schedules.
Consult your doctor before considering any peptide for personal use. Educational only, not administration guidance.
Common questions
What is 5-Amino-1MQ?
A small molecule that blocks an enzyme called NNMT, which is more active in fat cells. It shrank fat in mice but has not been tested in people. NNMT is an enzyme that is more active in fat tissue, especially with obesity. Blocking it appears to make fat cells burn more energy. 5-Amino-1MQ is often grouped with peptides but is actually a much smaller molecule.
What does the research say about 5-Amino-1MQ?
Obese mice on a high-fat diet lost fat mass and had smaller fat cells, without eating less. In fat cells in the lab, it raised energy use and reduced fat storage.
Is 5-Amino-1MQ FDA approved?
Not FDA-approved for human use.
What are the side effects of 5-Amino-1MQ?
No human safety data. Product quality varies widely.
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This page explains published research in plain language. It is not medical advice, a diagnosis, or a recommendation to take anything, and it does not give dosing. Most peptides here are not FDA-approved, and products sold online vary widely in purity. Rules around peptides are changing, so check the current status and talk with a licensed clinician before starting anything. Last reviewed 2026-10-19.